Motif ID: STAT5{A,B}.p2

Z-value: 0.983


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
STAT5Bchr17_-_40428391-0.414.3e-02Click!
STAT5Achr17_+_40440481-0.395.4e-02Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_44860798 3.732 NM_001083335
NM_013380
ZFP112

zinc finger protein 112 homolog (mouse)

chr19_+_44556163 3.466 NM_013361
ZNF223
zinc finger protein 223
chr19_+_35168558 2.872 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr19_+_44576266 2.091 NM_001037813
ZNF284
zinc finger protein 284
chr19_+_44645728 2.088 ZNF234
zinc finger protein 234
chr6_-_27440459 1.932 NM_007149
ZNF184
zinc finger protein 184
chr19_+_35225095 1.883 ZNF181
zinc finger protein 181
chr19_+_44669214 1.647 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
ZNF226




zinc finger protein 226




chr19_+_37709068 1.527 ZNF383
zinc finger protein 383
chr5_+_178450775 1.525 NM_001136116
ZNF879
zinc finger protein 879
chr19_+_44716683 1.254 NM_182490
ZNF227
zinc finger protein 227
chr5_+_178286913 1.190 NM_058230
ZNF354B
zinc finger protein 354B
chr19_-_40596781 1.150 NM_001010880
NM_001142577
NM_001142578
NM_001142579
ZNF780A



zinc finger protein 780A



chr19_-_37157718 1.140 NM_153257
ZNF461
zinc finger protein 461
chr19_+_35225479 1.059 NM_001029997
NM_001145665
ZNF181

zinc finger protein 181

chr11_-_82996898 1.025 CCDC90B
coiled-coil domain containing 90B
chr19_+_44331443 1.022 NM_181845
ZNF283
zinc finger protein 283
chr3_+_58484091 1.013 NM_153331
KCTD6
potassium channel tetramerisation domain containing 6
chr17_-_48945338 0.952 NM_001243877
TOB1
transducer of ERBB2, 1
chr19_+_44507076 0.950 NM_006300
ZNF230
zinc finger protein 230

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.35 5.63e-11 GO:0006355 regulation of transcription, DNA-dependent
2.26 4.51e-10 GO:0051252 regulation of RNA metabolic process
2.25 9.56e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.19 4.29e-10 GO:0010556 regulation of macromolecule biosynthetic process
2.13 5.13e-10 GO:0031326 regulation of cellular biosynthetic process
2.10 9.82e-10 GO:0009889 regulation of biosynthetic process
2.10 5.92e-09 GO:0010468 regulation of gene expression
2.00 4.72e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.99 1.47e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.74 3.30e-06 GO:0031323 regulation of cellular metabolic process
1.71 4.48e-05 GO:0060255 regulation of macromolecule metabolic process
1.70 3.22e-05 GO:0080090 regulation of primary metabolic process
1.60 2.56e-04 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.51 2.47e-06 GO:0005634 nucleus
1.31 2.82e-05 GO:0043231 intracellular membrane-bounded organelle
1.30 3.12e-05 GO:0043227 membrane-bounded organelle
1.28 7.80e-06 GO:0043229 intracellular organelle
1.28 9.36e-06 GO:0043226 organelle
1.18 4.00e-03 GO:0044424 intracellular part
1.17 3.01e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.57 4.72e-15 GO:0008270 zinc ion binding
2.36 1.52e-13 GO:0046914 transition metal ion binding
2.26 1.06e-11 GO:0003677 DNA binding
1.92 5.55e-10 GO:0003676 nucleic acid binding
1.72 7.40e-08 GO:0046872 metal ion binding
1.70 1.48e-07 GO:0043169 cation binding
1.70 1.72e-07 GO:0043167 ion binding